PHYTOCHEMICAL AND ANTIBACTERIAL ACTIVITY OF ZINGIBEROFFICINALE AGAINST SOME BACTERIAL CLINICAL ISOLATES

L Garba, A I Umar, M B Tijjani, M S Aliyu, M I Raji, S A Shinkafi, A B Adamu

Abstract


 Ginger (Zingiberofficinale ) has been used widely as a food spice and an herbal medicine. In particular, its gingerolrelated

components have been reported to possess antimicrobial and antifungal properties, as well as several

pharmaceutical properties. The phytochemical properties and antimicrobial activities of aqueous and methanolic

extract of ginger (Zingiber officinale ) were evaluated against some clinical isolates (Escherichia coli,

Streptococcus pneumoniae , Staphylococcus aureus  and Pseudomonas aeruginosa ) by agar well diffusion method.

Phytochemical screening revealed that the plant extract contained carbohydrates, flavonoids, cardiac glycosides,

saponins, tannins, alkaloids, terpenoids, but Anthraquinones was not detected. The extracts showed inhibitory

effects against some of the test organisms ranging from 8mm to 26mm at concentration range of 25mg/ml to

400mg/ml. The MIC values of aqueous and methanolic extract against the test organisms were; S. pneumoniae

 (100mg/ml and 200mg/ml) respectively, for E. coli  they were both 200mg/ml and for P. aeruginosa  25mg/ml for

the methanolic extract only. The MBC for aqueous and methanolic extract were for S. pneumonia  400mg/ml and

200mg/ml respectively, for E. coli  200mg/ml and 300mg/ml respectively, and P. aeruginosa  which was 50mg/ml

for the methanolic extract only. Findings suggest that the plant possess some antibacterial activity against the test

isolates and therefore further research is recommended on ginger plant in order to develop a more active antibiotic

for the treatment of diseases.

Keywords : Phytochemical, Antibacterial Activity, Zingiberofficinale , Bacteria


Full Text:

PDF

Refbacks

  • There are currently no refbacks.